产品名称

alpha Adducin抗体

英文名称

alpha Adducin

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K2806

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Rat, Chicken, Dog, Rabbit

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Monoclonal 

研究领域

肿瘤 细胞生物 信号转导 细胞骨架

蛋白细胞定位

细胞浆,细胞膜

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

发货地

上海

背景资料

Adducins are a family of cytoskeletal proteins encoded by three es (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct es but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.