商品属性：
|
产品名称
|
IRGM抗体
|
|
英文名称
|
IRGM
|
|
产品规格
|
50ul 100ul 200ul
|
|
产品货号
|
GOY-01K2732
|
|
产品分类
|
抗体 / 一抗
|
|
交叉反应
|
Human, Mouse, Rat, Dog
|
保存条件
|
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
|
|
标记
|
Unconjugated
|
抗体来源
|
Rabbit
|
|
抗体类型
|
Monoclonal
|
研究领域
|
细胞生物 **学 B-**细胞
|
|
蛋白细胞定位
|
细胞浆,细胞膜
|
纯化方法
|
affinity purified by Protein A
|
|
性状
|
Liquid
|
浓度
|
1mg/ml
|
|
储存液
|
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
|
发货地
|
上海
|
|
|
|
|
|
|
背景资料
|
IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathos. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.
|
公司正在出售的产品：
Anti-LDOC1/PEPE标记的癌症亮氨酸拉链下调因子1抗体Anti-LDOC1/PE，PE标记的癌症亮氨酸拉链下调因子1抗体
Anti-15 Lipoxygenase 1/PEPE标记的花生四烯酸15脂氧合酶1抗体Anti-15 Lipoxygenase 1/PE，PE标记的花生四烯酸15脂氧合酶1抗体
Anti-BMPR1A/PEPE标记的骨成型蛋白受体1A抗体Anti-BMPR1A/PE，PE标记的骨成型蛋白受体1A抗体
Anti-AKT3/PEPE标记的蛋白激酶B3Anti-AKT3/PE，PE标记的蛋白激酶B3
Anti-Integrin Alpha V + Beta 5/PEPE标记的整合素αVβ5抗体Anti-Integrin Alpha V + Beta 5/PE，PE标记的整合素αVβ5抗体
Anti-DAAM2/PEPE标记的形态发生紊乱关联激活因子2抗体Anti-DAAM2/PE，PE标记的形态发生紊乱关联激活因子2抗体
Anti-Phospho-SMAD7 (Ser249) /PEPE标记的磷酸化细胞信号转导分子SMAD7抗体Anti-Phospho-SMAD7 (Ser249) /PE，PE标记的磷酸化细胞信号转导分子SMAD7抗体
Anti-IL-1R2/PEPE标记的白介素1受体2抗体Anti-IL-1R2/PE，PE标记的白介素1受体2抗体
IRGM抗体Anti-UNCX/AF647AF647标记的同源蛋白UNCX抗体Anti-UNCX/AF647，AF647标记的同源蛋白UNCX抗体
Anti-phospho-VEGFR2 (Tyr1175)/AF647AF647标记的磷酸化血管内皮生长因子受体2抗体Anti-phospho-VEGFR2 (Tyr1175)/AF647，AF647标记的磷酸化血管内皮生长因子受体2抗体
Anti-HSPC014/C13orf12/AF647AF647标记的13号染色体开放阅读框12抗体Anti-HSPC014/C13orf12/AF647，AF647标记的13号染色体开放阅读框12抗体
Anti-Argonaute 4/AF647AF647标记的真核翻译起始因子2C4抗体Anti-Argonaute 4/AF647，AF647标记的真核翻译起始因子2C4抗体
Anti-RAVER2/AF647AF647标记的PTB结合核蛋白2抗体Anti-RAVER2/AF647，AF647标记的PTB结合核蛋白2抗体
Anti-UBE2D4/AF647AF647标记的泛素蛋白连接酶D4抗体Anti-UBE2D4/AF647，AF647标记的泛素蛋白连接酶D4抗体
Anti-SLC6A18/AF647AF647标记的溶质载体家族6成员18抗体Anti-SLC6A18/AF647，AF647标记的溶质载体家族6成员18抗体
Anti-FAM43B/AF647AF647标记的FAM43B蛋白抗体Anti-FAM43B/AF647，AF647标记的FAM43B蛋白抗体