产品名称

PCBP1抗体

英文名称

PCBP1

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K2647

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Pig, Cow, Horse

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Monoclonal 

研究领域

肿瘤 细胞生物 转录调节因子 表观遗传学

蛋白细胞定位

细胞核,细胞浆

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

发货地

上海

背景资料

This intronless e is thought to have been erated by retrotransposition of a fully processed PCBP-2 mRNA. This e and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire es. The protein encoded by this e appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxyase mRNA,