商品属性：
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产品名称
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SPRN抗体
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英文名称
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SPRN
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1876
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产品分类
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抗体 / 一抗
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交叉反应
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Mouse, Rat
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物 细胞凋亡 **及病毒
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蛋白细胞定位
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细胞膜
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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Prion diseases, or transmissible spongiform encephalopathies (TSEs), are manifested as etic, infectious or sporadic lethal neurodeerative disorders involving alterations of the prion protein (PrP). Constitutively expressed in normal brain, cellular PrP (PrP(C)) is sensitive to proteinase K digestion and is converted to the disease form, PrPSc, through alterations in protein folding conformation, which make it resistant proteases. SPRN (shadow of prion protein), also known as SHO or SHADOO, is a 151 amino acid cytoplasmic protein that is mainly expressed in brain. SPRN is considered a prion-like protein that has PrP(C)-like neuroprotective activity and may
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