商品属性:
产品名称
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Zyxin抗体
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英文名称
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Zyxin
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1945
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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染色质和核信号 神经生物学 信号转导 转录调节因子
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蛋白细胞定位
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细胞核,细胞浆,细胞膜
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in e expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
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