商品属性：
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产品名称
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VPREB1抗体
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英文名称
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VPREB1
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0141
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物 发育生物学 信号转导 干细胞 **细胞 B-**细胞
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蛋白细胞定位
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细胞外基质
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The e which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 es encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig e rearrangements in the early steps of B cell differentiation. In the mouse the two es are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two es are separate and do not belong to the same transcription unit.
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