商品属性：
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产品名称
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UNC5D抗体
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英文名称
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UNC5D
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0637
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物 神经生物学
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蛋白细胞定位
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细胞膜
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells. Additionally, when cleaved by a caspase to produce an intracellular fragment containing a death domain,UNC5H receptors induce apoptosis. This activity is blocked by the binding of netrin-1. In the absence of netrin-1, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion,
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