产品名称

TMEM166抗体

英文名称

TMEM166

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K1429

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Rat, Pig, Cow, Horse

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Polyclonal

研究领域

肿瘤 细胞生物  细胞凋亡

蛋白细胞定位

细胞浆,细胞膜

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

发货地

上海

背景资料

TMEM166, also known as FAM176A (family with sequence similarity 176, member A), is a 152 amino acid protein encoded by a e mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 es and making up approximately 8% of the human ome. A number of etic diseases are linked to es on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 e. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive etic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 e. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.