产品名称

APBB1 interacting protein 1抗体

英文名称

APBB1 interacting protein 1

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K1598

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Rat, Chicken, Pig, Cow, Sheep

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Polyclonal

研究领域

肿瘤 细胞生物 信号转导 结合蛋白 G蛋白偶联受体

蛋白细胞定位

细胞浆,细胞膜

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

发货地

上海

背景资料

APBB1IP is a 666 amino acid protein that contains one PH domain, one Ras-associating domain and belongs to the MRL family. Encoded by a e that maps to human chromosome 10p12.1, APBB1IP likely functions in signal transduction from Ras activation to Actin cytoskeletal remodeling. APBB1IP also suppresses insulin-induced promoter activities, by way of SRE and AP1. The two proline-rich regions of APBB1IP are necessary for AP1 transcription suppression. Ubiquitously expressed, with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes, APBB1IP is induced by all-trans-retinoic acid (ATRA) and mediates Rap 1-induced adhesion. APBB1IP also interacts with RAP 1A, Profilin-1, VASP and Mena.