产品名称

Procolla type I N terminal propeptide抗体

英文名称

Procolla type I N terminal propeptide

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K1521

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Rat, Dog, Cow, Horse, Sheep

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Polyclonal

研究领域

细胞生物

蛋白细胞定位

细胞外基质,分泌型蛋白

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

发货地

上海

背景资料

This e encodes the pro-alpha1 chains of type I colla whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming colla found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this e are associated with osteoesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this e and the e for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this e. [provided by R. Dalgleish, Feb 2008].