Vincristine sulfate
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产品名称:
Vincristine sulfate
产品型号:
GOY-Y3282
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-05
简单介绍
Vincristine sulfate≥ 46.15mg/mL in DMSO
Vincristine sulfate
的详细介绍
性能参数
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产品名称
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Vincristine sulfate
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规格
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10mM (in 1mL DMSO) 5mg 25mg 100mg
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货号
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GOY-Y3282
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含量
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>98.00%
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CAS
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2068-78-2
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别名
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化学名
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分子式
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C46H58N4O14S
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分子量
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分子量 923.04
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溶解度
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≥ 46.15mg/mL in DMSO
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储存条件
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4°C, protect from light
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Vincristine is a naturally occurring alkaloid that potently inhibits the tubulin addition with the inhibition constant Ki value of 0.085 μM and exhibits an anti-proliferative activity against B16 melanoma cells with the half maximal inhibition concentration IC50 value of 0.45 M [1].
Vincristine is extracted from leaves of the periwinkle plant Catharanthus roseus (L.) G. Don of the family Apocynaceae and has an asymmetric structure consisting of two dimers, a dihydroindole nucleus (vindoline) and an indole nucleus (catharanthine), that are linked by a carbon-carbon bond [2].
Vincristine has been found to be active against a wild range of malignancies, including acute lymphoblastic leukemia (ALL), acute non-lymphoblastic leukemia (ANLL), non-Hodgkin lymphoma (NHL), Hodgkin’s disease and brain tumors [2].
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