性能参数
产品名称
Pranoprofen
规格
10mM (in 1mL DMSO) 50mg
货号
GOY-Y3142
含量
>98.00%
CAS
52549-17-4
别名
化学名
2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
分子式
C15H13NO3
分子量
分子量 255.27
溶解度
≥ 11.5mg/mL in DMSO
储存条件
Store at -20°C
General tips
用途
仅供科研
价格
电询
详细内容
Pranoprofen is a non-steroidal anti-inflammatory drug used in ophthalmology. Target: PGE2Pranoprofen 0.1% was found to be as effective as diclofenac sodium 0.1% in reducing inflammation and pain after strabismus surgery. Pranoprofen could be used as a safe and effective anti-inflammatory alternative for the treatment of inflammation following strabismus surgery [1]. pranoprofen has efficacy equivalent to a moderate-potency corticosteroid with a better safety profile. It should be considered for the treatment of chronic conjunctivitis of presumed nonbacterial origin [2]. Pranoprofen inhibited ER stress-induced glucose regulated protein 78 (GRP78) expression, an ER-localized molecular chaperon. Moreover, pranoprofen inhibited ER stress-induced CCAAT/enhancer-binding protein homologous protein (CHOP) expression, an apoptotic transcription factor. the inhibitory effect of pranoprofen on ER stress-related genes (GRP78 and CHOP) would be mediated through the inhibition of XBP-1 splicing [3].
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产品均为实验试剂,仅供科研实验使用,非药品、非食品、不可用于动物及人体!