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Trolox

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产品名称: Trolox
产品型号: GOY-Y2846
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-05-04

简单介绍

TroloxDMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 3 mg/ml


Trolox  的详细介绍

性能参数

产品名称

Trolox

规格

250mg 500mg 1g

货号

GOY-Y2846

 含量

>98.00%

CAS

53188-07-1

别名

N/A

 

 

化学名

N/A

分子式

C14H18O4

分子量

分子量 250.3

溶解度

DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 3 mg/ml

储存条件

Store at -20°C

General tips

 

用途

仅供科研

价格

电询

详细内容

Trolox is a vitamin E analogue and is a powerful antioxidant.

Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion[1]. Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or posttreatment of cells with Trolox reduced H2O2-induced DNA fragmentation to control levels and below. [2]. Trolox is a hydrophilic analogue of alpha-tocopherol and reported to scavenge peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. Trolox prolongs substantially the survival of human ventricular myocytes and hepatocyte against oxyradicals generated with xanthine oxidase plus hypoxanthine, and prevented lysis of red cells exposed to an azo-initiator[3].

 

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