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PluriSIn #1

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产品名称: PluriSIn #1
产品型号: GOY-Y2784
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-28

简单介绍

PluriSIn #1 ≥ 6.75 mg/mL in DMSO, ≥ 15.67 mg/mL in EtOH with ultrasonic and warming


PluriSIn #1  的详细介绍

性能参数

产品名称

PluriSIn #1 

规格

10mM (in 1mL DMSO) 10mg 50mg

货号

GOY-Y2784

 含量

>98.00%

CAS

91396-88-2

别名

N/A

 

 

化学名

N'-phenylpyridine-4-carbohydrazide

分子式

C12H11N3O

分子量

分子量 213.24

溶解度

≥ 6.75 mg/mL in DMSO, ≥ 15.67 mg/mL in EtOH with ultrasonic and warming

储存条件

Store at -20°C

General tips

 

用途

仅供科研

价格

电询

详细内容

NSC 14613 is a pluripotent cell-specific inhibitor (PluriSIn) that selectively eliminates human pluripotent stem cells (hPSCs) leaving a large array of progenitor and differentiated cells unaffected. Among 15 identified PluriSIns, NSC 14613 (also known as PluriSIn #1) is a derivative of N-acyl phenylhydrazine that shares a common structure moiety, phenylhydrazine (Ph-N[H,C]-NH) with 9 other PluriSIns. NSC 14613 is also an inhibitor of stearoyl-coA desaturase (SCD1) that inhibits the activity of SCD1 in hPSCs causing the imbalance between substrates and products and subsequently resulting in the accumulation of palmitate and stearate and the deprivation of oleate. Study results have suggested that NSC 14613 is able to induce ER stress, protein synthesis attenuation and apoptosis in hPSCs and can be used to prevent teratoma formation from tumorigenic undifferentiated cells.

 

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NSC 62598710mg 50mg>98.00%Cas No. 141992-47-4C15H13NO2S

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PalMitoyl Tripeptide-11g 5g>98.00%Cas No. 147732-56-7C30H54N6O5

 


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