性能参数
产品名称
Linderalactone
规格
1mg 5mg 10mg
货号
GOY-Y2735
含量
>98.00%
CAS
728-61-0
别名
N/A
化学名
分子式
C15H16O3
分子量
分子量 244.29
溶解度
DMSO: 50 mg/mL (204.67 mM)
储存条件
-20°C, protect from light
General tips
用途
仅供科研
价格
电询
详细内容
Linderalactone is an important sesquiterpene lactone isolated from Radix linderae. Linderalactone inhibits cancer growth by modulating the expression of apoptosis-related proteins and inhibition of JAK/STAT signalling pathway. Linderalactone also inhibits the proliferation of the lung cancer A-549 cells with an IC50 of 15 μM[1][2].
Linderalactone (0-100 μM; 24 hours; A549 cells) treatment inhibits the growth of A549 cells concentration-dependently. The IC50 of linderalactone is 15 μM[1].Linderalactone (7.5-30 μM; A549 cells) treatment induces apoptosis in A549 cells in a dose-dependent manner[1].Linderalactone (7.5-30 μM; 24 hours; A549 cells) treatment induces G2/M cell cycle arrest of A549 cells dose-dependently[1].Linderalactone (7.5-30 μM; A549 cells) inhibits the expression of STAT1, JAK1 and JAK2. Linderalactone could also inhibit the phosphorylation of pSTAT1, pSTAT-2, pJAK1 and pJAk2[1]. Cell Viability Assay[1] Cell Line: Lung cancer A549 cells
[1]. Deng Y, et al. Linderalactone inhibits human lung cancer growth by modulating the expression of apoptosis-related proteins, G2/M cell cycle arrest and inhibition of JAK/STAT signalling pathway. J BUON. 2019 Mar-Apr;24(2):566-571. [2]. Qinghua Sun, et al. Preparative Isolation and Purification of Linderalactone and Lindenenol from Radix linderae by HSCCC. Journal of Liquid Chromatography & Related Technologies. Aug 2005:113-121.
公司正在销售的产品:
铬酸钾 CP 氯离子(Cl-)标准溶液 100μg/mL,基体:水
铬酸钾 GR 铈标准溶液 1000μg/ml
铬酸钾 PT 铈标准溶液 1000μg/ml,基体:10%HNO3
铬酸钾 SP 色度标准溶液 500度
铬酸钾 99.99% metals basis 化学耗氧量(COD)-铬法标准溶液 1000μg/ml
铬酸钾 ACS 氰化物标准溶液 1.000 g/L in H2O
Relebactam1mg 5mg 10mg 25mg 50mg>98.00%Cas No. 1174018-99-5C12H20N4O6S
RIG-1 modulator 110mM*1mLinDMSO 1mg 5mg 10mg 50mg>98.00%Cas No. 1428729-63-8C14H17N5OS2
Ribocil-C10mM*1mLinDMSO 5mg 10mg 50mg 100mg>98.00%Cas No. 1825355-56-3C21H21N7OS
Ribocil B (Ribocil S enantiomer)2mg 5mg 10mg 50mg 100mg>98.00%Cas No. 1825355-55-2C19H22N6OS
RO-91875mg 10mM*1mL in Water 50mg 100mg 200mg>98.00%Cas No. 876708-03-1C9H12N6O5
传真号码:021-39596320 021-39921927
QQ: 3004918891 3004905818 3004901493 移动电话:18321818584 15026555973 地址:上海松江新砖公路1155号
产品均为实验试剂,仅供科研实验使用,非药品、非食品、不可用于动物及人体!