性能参数
产品名称
Larotaxel
规格
1mg 5mg 10mg
货号
GOY-Y2734
含量
>98.00%
CAS
156294-36-9
别名
N/A
化学名
分子式
C45H53NO14
分子量
分子量 831.9
溶解度
DMSO: ≥ 50 mg/mL (60.10 mM)
储存条件
Store at -20°C
General tips
用途
仅供科研
价格
电询
详细内容
Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel[1][2][3].
[1]. Diéras V, et al. Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy. Ann Oncol. 2008 Jul;19(7):1255-60. [2]. Morris PG, et al. Novel anti-tubulin cytotoxic agents for breast cancer. Expert Rev Anticancer Ther. 2009 Feb;9(2):175-85. [3]. Zatloukal P, et al. Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIIB or stage IV non-small cell lung cancer. J Thorac Oncol. 2008 Aug;3(8):894-901.
公司正在销售的产品:
溴化钾 FT-IR grade, ≥99.5% 钴标准溶液100?g/ml,基体: 1%硝酸
溴化钾 99.997% metals basis 铯标准溶液 1000μg/ml
溴化钾 分析标准品,99.94% 六价铬标准溶液 六价铬标准溶液 1000μg/ml
氟化钾,无水 GR,粉末 氯离子标准溶液1000μg/ml
氟化钾,无水 99.9% metals basis 氯离子标准溶液500mg/L,溶剂:水
铬酸钾 AR 氯离子(Cl-)标准溶液 1000μg/mL,基体:水
Q2031mg 5mg 10mg 50mg 100mg>98.00%Cas No. 1334719-95-7C29H28ClF3N4O2
Pyrithione5mg 10mg 25mg 50mg 100mg>98.00%Cas No. 1121-30-8C5H5NOS
Pyrantel Pamoate10mM (in 1mL DMSO) 10mg 25mg 50mg 100mg>98.00%Cas No. 22204-24-6C23H16O6.C11H14N2S
Retro-210mM 1 mL in DMSO 5mg 10mg 50mg 100mg>98.00%Cas No. 1429192-00-6C19H16N2OS
Resiquimod (R-848)10mM (in 1mL DMSO) 10mg 25 mg 50mg 100mg>98.00%Cas No. 144875-48-9C17H22N4O2
Remdesivir (GS-5734)10 mM * 1 mL in DMSO 5mg 10mg 50mg 100mg>98.00%Cas No. 1809249-37-3C27H35N6O8P
传真号码:021-39596320 021-39921927
QQ: 3004918891 3004905818 3004901493 移动电话:18321818584 15026555973 地址:上海松江新砖公路1155号
产品均为实验试剂,仅供科研实验使用,非药品、非食品、不可用于动物及人体!