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Picrocrocin

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产品名称: Picrocrocin
产品型号: GOY-Y2666
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-28

简单介绍

PicrocrocinN/A


Picrocrocin  的详细介绍

性能参数

产品名称

Picrocrocin

规格

1mg 5mg

货号

GOY-Y2666

 含量

>98.00%

CAS

138-55-6

别名

N/A

 

 

化学名

N/A

分子式

C16H26O7

分子量

分子量 330.37

溶解度

N/A

储存条件

4°C, protect from light

General tips

 

用途

仅供科研

价格

电询

详细内容

Picrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells[1].

Picrocrocin exerted growth inhibitory effects on the SK-MEL-2 melanoma cells. The IC50 of picrocrocin against the SK-MEL-2 cells was 20 μM at 24-h incubation. The antiproliferative activity of picrocrocin was due to apoptosis and cell cycle arrest. In addition, picrocrocin enhanced the ROS levels and decreased the MMP levels of SK-MEL-2 cells. Finally, picrocrocin inhibited the JAK/STAT5 signalling pathway in the SK-MEL-2 melanoma cells[1].

[1]. Yu L, et al. Picrocrocin exhibits growth inhibitory effects against SKMEL- 2 human malignant melanoma cells by targeting JAK/ STAT5 signaling pathway, cell cycle arrest and mitochondrial mediated apoptosis. J BUON. 2018 Jul-Aug;23(4):1163-1168.

 

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