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Perindopril Erbumine

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产品名称: Perindopril Erbumine
产品型号: GOY-Y2659
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-28

简单介绍

Perindopril Erbumine≥ 15.7mg/mL in Ethanol , ≥ 8.58 mg/mL in DMSO with ultrasonic, ≥ 111.4 mg/mL in H2O


Perindopril Erbumine  的详细介绍

性能参数

产品名称

Perindopril Erbumine

规格

10mM (in 1mL DMSO) 100mg

货号

GOY-Y2659

 含量

>98.00%

CAS

107133-36-8

别名

N/A

 

 

化学名

(2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;2-methylpropan-2-amine

分子式

C19H32N2O5.C4H11N

分子量

分子量 441.6

溶解度

≥ 15.7mg/mL in Ethanol , ≥ 8.58 mg/mL in DMSO with ultrasonic, ≥ 111.4 mg/mL in H2O

储存条件

Store at RT

General tips

 

用途

仅供科研

价格

电询

详细内容

Perindopril erbumine (Perindopril tert-butylamine salt) is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.Target: ACEPerindopril is a long-acting ACE inhibitor. It is used to treat high blood pressure, heart failure or stable coronary artery disease in form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (trade name Aceon). According to the Australian government's Pharmaceutical Benefits Scheme website, based on data provided to the Australian Department of Health and Aging by the manufacturer, perindopril arginine and perindopril erbumine are therapeutically equivalent and may be interchanged without differences in clinical effect. However the dose prescribed to achieve the same effect will differ due to different molecular weights for the two forms. Perindopril is one of the most prescribed inhibitors of angiotensin converting enzyme, has a large evidence base, which allows to use it in patients with hypertension, diabetes mellitus type 2, coronary heart disease and chronic heart failure. In this review, the author focused on the evidence of organoprotecting properties of perindopril that lie outside lowering blood pressure.

 

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