性能参数

产品名称

MIRA-1

规格

10mg 50mg

货号

GOY-Y2629

 含量

>98.00%

CAS

72835-26-8

别名

NSC 19630

化学名

1-[(1-oxopropoxy)methyl]-1H-pyrrole-2,5-dione

分子式

C8H9NO4

分子量

分子量 183.16

溶解度

18.3mg/mL in ethanol, or in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

MIRA-1 is a maleimide-derived small molecule that reactivates the tumor suppressor function of mutant p53, inducing apoptosis in several human solid tumor cell lines carrying tetracycline-regulated mutant p53 (IC50 = 10 μM in vitro).1 Treatment of tumor cells with MIRA-1 induces p21, MDM2 and PUMA in a mutant p53-dependent manner.[1] At a concentration of 5-10 mg/kg, MIRA-1, alone or in combination with dexamethasone , arrested tumor growth in a mouse xenograft model of multiple myeloma.[2]

硝酸钙,四水  用于植物细胞培养，99%  苯并(b)荧蒽标准溶液 10～100μg/mL，基体：甲醇

硝酸钙 用于细胞培养，99%  苯并(k)荧蒽标准溶液 4.38ug/ml,基体:甲醇

乙酸钙 AR,99%  苯甲酸标准溶液 1.00mg/ml，基体：石油醚

乙酸钙 CP,98%  苯甲酸标准溶液 1.00mg/mL，基体：乙醇-水

乙酸钙 ACS, ≥99.0%  溴标准溶液 100μg/mL

磷酸二氢钙 AR,92%  苯纯度分析标准物质 99.95％

Lipoxamycin hemisulfate10mM*1 mL in DMSO 5mg 10mg 25mg>98.00%Cas No. 11075-87-9C19H36N2O5.1/2H2O4S

Linezolid10mM (in 1mL DMSO) 10mg 25mg 100mg>98.00%Cas No. 165800-03-3C16H20FN3O4

LolCDE-IN-15mg 10mg 50mg 100mg>98.00%Cas No. 1639933-78-0C21H16FN3O

Lumefantrine (Benflumetol)10mg 50mg 100mg 500mg>98.00%Cas No. 82186-77-4C30H32Cl3NO

LtaS-IN-15mg 10mg 50mg 100mg>98.00%Cas No. 877950-01-1C24H17N3O5

Magnoflorine5mg 10mg 25mg 50mg>98.00%Cas No. 2141-09-5C20H24NO4