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Malachite green oxalate

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产品名称: Malachite green oxalate
产品型号: GOY-Y2622
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-28

简单介绍

Malachite green oxalateDMSO: 25 mg/mL (53.94 mM)


Malachite green oxalate  的详细介绍

性能参数

产品名称

Malachite green oxalate

规格

10mM*1 mL in DMSO 100mg

货号

GOY-Y2622

 含量

>98.00%

CAS

2437-29-8

别名

N/A

 

 

化学名

N/A

分子式

C23H25N2.1/2C2H2O4.C2HO4

分子量

分子量 463.5

溶解度

DMSO: 25 mg/mL (53.94 mM)

储存条件

4°C, stored under nitroge

General tips

 

用途

仅供科研

价格

电询

详细内容

Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green oxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green oxalate exhibits antitumor activity in vitro and in vivo[1][2][3].

[1]. Kozuka S, et, al. Permeability of dormant spores of Bacillus subtilis to malachite green and crystal violet. J Gen Microbiol. 1991 Mar; 137(3): 607-13. [2]. Takahashi S, et, al. Reversible off-on fluorescence probe for hypoxia and imaging of hypoxia-normoxia cycles in live cells. J Am Chem Soc. 2012 Dec 5; 134(48): 19588-91. [3]. Liu T, et, al. Identification of an IKBKE inhibitor with antitumor activity in cancer cells overexpressing IKBKE. Cytokine. 2019 Apr; 116: 78-87.

 

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