性能参数

产品名称

Lidocaine hydrochloride (Lignocaine hydrochloride)

规格

5g 10mM*1mLinWater

货号

GOY-Y2617

 含量

>98.00%

CAS

73-78-9

别名

N/A

化学名

N/A

分子式

C14H23ClN2O

分子量

分子量 270.8

溶解度

H2O : ≥ 36 mg/mL (132.94 mM)

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Lidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide-type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90-120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes).

[1]. VAN DER Wal S, et al. Lidocaine increases the anti-inflammatory cytokine IL-10 following mechanical ventilation in healthy mice. Acta Anaesthesiol Scand. 2014 Oct 14. [2]. Acevedo-Arcique CM, et al. Lidocaine, dexmedetomidine and their combination reduce isoflurane minimum alveolar concentration in dogs. PLoS One. 2014 Sep 18;9(9):e106620.

乙酸钡 99.99% metals basis  L-亮氨酸 99%

铬酸钡 AR,98.0%  硫酸新霉素 USP级,680 I.U./mg

铬酸钡 99.999% metals basis  硫酸新霉素 分析标准品

过氧化钡 AR,85.0%  硫酸新霉素 USP级

过氧化钡 CP,85.0%  L-缬氨酸 99%

过氧化苯甲酰 AR,99.0%  活性炭 AR，200目，粉末状，褐色

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