性能参数

产品名称

Lometrexol

规格

1mg 5mg

货号

GOY-Y2615

 含量

>98.00%

CAS

106400-81-1

别名

N/A

化学名

N-[4-[2-[(6R)-2-amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]-L-glutamic acid

分子式

C21H25N5O6

分子量

分子量 443.5

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation.

柠檬酸铵 GR  150p塑料瓶,用于盛装固体,白色,供货商型号BP-10,φ51.8*95

硫酸高铁铵,十二水 99.95% metals basis  黑色瓶盖,匹配2ml棕色螺纹玻璃瓶,φ12.5*9.2

硫酸镍铵，六水 99.9% metals basis  黑色瓶盖,匹配3ml棕色螺纹玻璃瓶,φ15.7*10.2

碱性品红 Biological stain  500p塑料瓶,用于盛装固体,白色,供货商型号BP-69,φ75*137.7

碱性品红 Indicator，pH 1.0-3.1  42M?

MtbHU-IN-1250mg 500mg>98.00%Cas No. 59736-84-4C44H36N4O12S2

MPro N35mg 25mg>98.00%Cas No. 884650-98-0C35H48N6O8

N-Desmethylclozapine10mg 50mg>98.00%Cas No. 6104-71-8C17H17ClN4

Narasin (sodium salt)5mg 25mg>98.00%Cas No. 58331-17-2C43H71O11 ? Na

Nalidixic acid10mM (in 1mL DMSO) 50mg>98.00%Cas No. 389-08-2C12H12N2O3

Naftifine HCl50mg 500mg>98.00%Cas No. 65473-14-5C21H21N.HCl

Nafcillin Sodium10mM (in 1mL DMSO) 50mg>98.00%Cas No. 7177-50-6C21H21N2O5S.H2O.Na