性能参数

产品名称

UZH1a

规格

5 mg

货号

GOY-Y2607

 含量

>98.00%

CAS

N/A

别名

N/A

化学名

N/A

分子式

C32H42N6O3

分子量

分子量 558.71

溶解度

DMSO : 80 mg/mL (143.19 mM; Need ultrasonic)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1a can be used for epitranscriptomic modulation of cellular processes. UZH1a has antitumor activity. UZH1a also can be used as a chemical probe for studying METTL3[1].

UZH1a (2.5-160 μM; 72 h) inhibits the growth of MOLM-13, HEK293T, and U2Os cells, with IC50s of 11 μM, 67 μM, and 87 μM, respectively[1].UZH1a (2.5-100 μM; 16 h) reduces m6A methylation level in mRNA from MOLM-13 cells in a dose-dependent manner (IC50=4.6 μM)[1].UZH1a (40 μM; 16 h) reduces m6A methylation level in mRNA from MOLM-13, HEK293T, and U2Os cells[1].UZH1a (20 μM; 16 h) increases apoptosis and leads to cell cycle arrest in MOLM-13 cells[1].

[1]. Moroz-Omori EV, et, al. METTL3 inhibitors for epitranscriptomic modulation of cellular processes. bioRxiv. 2020 Oct 13.

氯化铝,六水 99.99% metals basis  甲基丙烯酸缩水甘油酯 98%

氟化氢铵 AR,98.5%         甲基丙烯酸羟乙酯 96%

氟化氢铵 CP,97.00%  氨苄青霉素，三水 96%

氟化氢铵 99.99% metals basis  两性霉素B 80%，750 μg/mg

磷酸氢二铵 AR,98.5%  杆菌肽 效价 >60 Units/mg

磷酸氢二铵 99.99% metals basis  杆菌肽锌  from Bacillus licheniformis, ~70,?

Nigranoic acid5mg>98.00%Cas No. 39111-07-4C30H46O4

Nicarbazin500 mg>98.00%Cas No. 330-95-0C19H18N6O6

Nonanoic Acid100 mg>98.00%Cas No. 112-05-0C9H18O2

Nitroxynil1 g>98.00%Cas No. 1689-89-0C7H3IN2O3

Nimorazole1mg>98.00%Cas No. 6506-37-2C9H14N4O3

Lactoferrin (17-41) TFA1mg 5mg>98.00%Cas No. N/AC143H225F3N46O31S3