性能参数

产品名称

Troglitazone

规格

Troglitazone

货号

GOY-Y2603

 含量

>98.00%

CAS

97322-87-7

别名

Rezulin;CS-045;Noscal

化学名

5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

分子式

C24H27NO5S

分子量

分子量 441.54

溶解度

≥ 20.9 mg/mL in DMSO, ≥ 3.34 mg/mL in EtOH with ultrasonic and warming

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Peroxisome proliferator-activated receptor gamma (PPARγ) agonists and PPARg/a dual agonists are used in the treatment of type 2 diabetes mellitus. Troglitazone is a prototypical sarcomagenic PPARg agonist.

In vitro: Troglitazone PPARγ ligands showed potent inhibitory effect on proliferation, and could induce RCC cell apoptosis, suggesting that the PPARγ ligands have potential antitumor effects on renal carcinoma cells [1].

In vivo: Troglitazone increased EC proliferation in brown and white adipose tissue and liver in mice at sarcomagenic doses (400 and 800 mg/kg) after four weeks of treatment [2].

Clinical trial: Several clinical trials have been conducted to investigate the efficacy, safety and pharmacokinetics of troglitazone in the liposarcoma and diabtes mellitus patients [3].

偏钒酸铵 99.999% (metals basis)  1,1,2-**基-1H-苯并[e]吲哚 98%

偏钒酸铵 99.9%metals basis  5,6,7,8-四氢-2-甲基喹啉 98%

硫酸铝，十八水 99.95% metals basis  费舍尔氏醛(W醛) 97%

乙酸铵 AR  5-氯-1.3.3-**基-2-亚甲基吲哚啉 98%

乙酸铵 CP  邻甲氧基苯胺 CP,97%

乙酸铵 GR，≥99.0%  邻甲氧基苯胺 GR,99%

L-Triguluronic acid5mg>98.00%Cas No. 66754-14-1C18H26O19

L-Diguluronic acid5mg>98.00%Cas No. 34044-54-7C12H18O13

Levofloxacin25mg>98.00%Cas No. 100986-85-4C18H20FN3O4

Liranaftate10mg>98.00%Cas No. 88678-31-3C18H20N2O2S

Lincomycin HCl50mg>98.00%Cas No. 859-18-7C18H34N2O6S.HCl

LF 111mg>98.00%Cas No. 832729-13-2C69H112N26O14