性能参数

产品名称

K-TMZ

规格

1mg 5mg 10mg

货号

GOY-Y2554

 含量

>95.00%

CAS

N/A

别名

N/A

化学名

N/A

分子式

C7H7N5O2

分子量

分子量 193.2

溶解度

DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

K-TMZ is a DNA alkylating agent. It increases the concentration of O6-methylated deoxyguanosine in U87 glioblastoma multiforme (GBM) cells in a concentration-dependent manner. K-TMZ reduces cell viability of GBM cell lines lacking (IC50s = 18-44 μM) or expressing O6-methylguanine DNA methyltransferase (MGMT; IC50s = 115-240 μM). K-TMZ can cross the blood-brain barrier and increases survival in a Br23c mouse xenograft model of GBM when administered at a dose of 14.9 mg/kg.

羟丙基甲基纤维素 2%粘度6mPa.s;甲氧基28-30%;羟丙基7.0-12%  对位红 98%

羟丙基甲基纤维素 2%粘度15mPa.s;甲氧基28-30%;羟丙基7.0-12%  偏钒酸钾 99.9% metals basis

羟丙基甲基纤维素 II型，粘度：4000mPa.s  苯酚红钠盐 AR

羟丙基甲基纤维素 II型，粘度：15000mPa.s  戊四唑 98%

羟丙基甲基纤维素 II型，粘度：100000mPa.s  五氯苯酚 Standard for GC

4-硝基邻苯二胺 97%  五氯?

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