性能参数

产品名称

Jacaric Acid

规格

1mg 5mg 10mg

货号

GOY-Y2552

 含量

>95.00%

CAS

28872-28-8

别名

N/A

化学名

N/A

分子式

C18H30O2

分子量

分子量 278.4

溶解度

DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 100 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid . Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 μM). It increases the production of reactive oxygen species, and cytotoxicity is abolished by the antioxidant α-tocopherol, suggesting that apoptosis results from oxidative stress. Jacaric acid is metabolized in vivo to conjugated linoleic acid , which is also cytotoxic to cancer cells. Jacaric acid inhibits cyclooxygenase-1 in vitro (Ki = 1.7 μM) and, with long term feeding, decreases stearoyl-CoA desaturase expression and activity in mice.

红四氮唑 98%  油酸 分析标准品，≥99.0% (GC)

乙酰丙酮钒 97%  1,7-辛二炔  98%

二甲酚橙四钠盐 AR  十八烷 99%

二乙基二硫代氨基甲酸锌 98%  十八烷 分析标准品，≥99.5% (GC)

氟化锌,四水  98%  十八烷 Standard for GC, ≥99.5% (GC)

环戊醇 99%  丙酮基三苯基氯化膦 99%

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