性能参数

产品名称

Kazusamycin B

规格

100μg 500μg

货号

GOY-Y2548

 含量

>95.00%

CAS

107140-30-7

别名

N/A

化学名

N/A

分子式

C32H46O7

分子量

分子量 542.7

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Kazusamycin B is a bacterial metabolite originally isolated from Streptomyces. It has antifungal activity against S. pombe and R. javanicus (MICs = 0.05 and 2.13 μg/ml, respectively) but is inactive against Gram-positive and Gram-negative bacteria (MICs = >100 μg/ml). Kazusamycin B (5 ng/ml) halts the cell cycle at the G1 phase and induces nuclear condensation in L1210 cells, as well as inhibits nuclear-to-cytosolic transport of the HIV-1 regulatory protein Rev in HeLa cells expressing Rev (IC50 = 6.3 nM). It is cytotoxic to L1210 and HCT-8 cells with IC50 values of 1.8 and 1.6 ng/ml, respectively, and reduces tumor growth in a variety of murine tumor and mouse xenograft models.

广泛PH试纸(pH9-14) 9-14 80条/盒  铌粉 99.95% metals basis,325目

氟化铅 AR,99.5%   α-萘酚醌苯基甲烷 90%

氟化铅 SP  1-萘甲胺 98%

醋酸铅试纸 80条/盒,10盒/箱  壬基酚 分析标准品

氟硅酸镁 CP,98.0%  2,9-二甲基-1,10-菲啰啉盐酸盐 99%

氟化镁 CP，95.0%  1-萘酚酞 高纯级

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