性能参数

产品名称

GSK2983559 free acid

规格

1mg 5mg 10mg 25mg 50mg 100mg

货号

GOY-Y2520

 含量

>98.00%

CAS

1579965-12-0

别名

N/A

化学名

N/A

分子式

C21H23N4O7PS2

分子量

分子量 538.53

溶解度

DMSO: 5 mg/mL (9.28 mM; ultrasonic and warming and heat to 80°C)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

GSK2983559 free acid (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor. GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples[1].

[1]. Haile PA, et al. Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. J Med Chem. 2019 Jul 25;62(14):6482-6494.

(+)-芸香苷，三水 97%  4-氟吲哚 98%

曲克芦丁 97%  间氟-DL-酪氨酸 99%

苯磺酰氯 98%  法呢醇 96%

单氰胺 50%水溶液,含0.1 %甲酸稳定剂  3-羧基苯甲醛 97%

8-羟基喹啉 AR,99.0%  3-氟-5-(三氟甲基)苯甲腈 97%

8-羟基喹啉 分析标准品，>99.5%(GC)  2-氟-5-甲氧基苯甲醛 AR

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