性能参数

产品名称

Kinetin riboside

规格

10mM*1mL in DMSO 100mg 200mg 500mg

货号

GOY-Y2500

 含量

>98.00%

CAS

Cas No. 4338-47-0

别名

N/A

化学名

N/A

分子式

C15H17N5O5

分子量

分子量 347.33

溶解度

DMSO: ≥ 29 mg/mL (83.49 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM. IC50: 2.5 μM (HCT-15 cells)[1]

Kinetin riboside displays antiproliferative and apoptogenic activity against various human cancer cell lines. Kinetin riboside is able to inhibit the proliferation in HCT-15 human colon cancer cells in a dose-dependent manner (IC50=2.5 μM)[1]. Kinetin riboside induces apoptosis in HeLa and mouse melanoma B16F-10 cells. Kinetin riboside disrupts the mitochondrial membrane potential and induces the release of cytochrome c and activation of caspase-3. Bad are up-regulated while Bcl-2 is down-regulated under kinetin riboside exposure[2].

Kinetin riboside significantly suppresses tumor growth. The most effective anti-melanoma response is elicited at 40 mg/kg[2].

[1]. Rajabi M, et al. Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line. Nucleosides Nucleotides Nucleic Acids. 2012;31(6):474-81. [2]. Choi BH, et al. Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells. Cancer Lett. 2008 Mar 8;261(1):37-45.

熊去氧胆酸 分析标准品  色标Standard for GC ,≥99.0%

芝麻素 分析标准品  邻氯苯氧乙酸  98%

磷酸钴  98%  6-氯-1-己烯 97%

3,3'-二氨基联苯胺 97%  4-氯苄胺 98%

联大茴香胺盐酸盐 CP,96%  冰晶石  天然矿物,晶粒,大约 0.06-19in

2,2',5,5'-四氯代联苯胺 99%  2,4-二氯硝基苯 97%

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Antibacterial compound 21mg 5mg 10mg>98.00%Cas No. 170104-58-2C22H30FN5O6

Anti-parasitic agent 3100mg 250mg 500mg>98.00%Cas No. N/AC21H22FN5O3

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