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Isoliensinine

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产品名称: Isoliensinine
产品型号: GOY-Y2497
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-27

简单介绍

IsoliensinineDMSO: 250 mg/mL (409.34 mM)


Isoliensinine  的详细介绍

性能参数

产品名称

Isoliensinine

规格

1mg 5mg 10mg 20mg

货号

GOY-Y2497

 含量

>98.00%

CAS

Cas No. 6817-41-0

别名

N/A

 

 

化学名

N/A

分子式

C37H42N2O6

分子量

分子量 610.74

溶解度

DMSO: 250 mg/mL (409.34 mM)

储存条件

4°C, protect from light

General tips

 

用途

仅供科研

价格

电询

详细内容

Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells[1][2].

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation[1].Isoliensinine exerts antiproliferative effect on CASMCs induced by phenylephrine, and its mechanisms are related to decrease the overexpression of growth factors (PDGF-beta, bFGF), protooncogene (c-fos, c-myc) and hsp70[3].

[1]. Zhang X, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015 Jul 29;5:12579. [2]. Xiao JH, et al. Effects of isoliensinine on proliferation of porcine coronary arterial smooth muscle cells induced by phenylephrine. Yao Xue Xue Bao. 2005 Feb;40(2):105-10.

 

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