性能参数

产品名称

JS-K

规格

1mg 5mg

货号

GOY-Y2458

 含量

>98.00%

CAS

Cas No. 205432-12-8

别名

N/A

化学名

4-[2-(2,4-dinitrophenoxy)-1-oxidodiazenyl]-1-piperazinecarboxylic acid, ethyl ester

分子式

C13H16N6O8

分子量

分子量 384.3

溶解度

DMF: 0.5 mg/ml,DMSO: 0.3 mg/ml,Ethanol: slightly soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

JS-K is a nitric oxide (NO) donor that reacts with glutathione to generate NO at physiological pH. It inhibits proliferation of HL-60 cells (IC50 = 0.5 uM), which is prevented by the glutathione precursor N-acetyl-L-cysteine , and inhibits growth of the solid tumor cell lines PPC-1, DLD-1, and Meth A. It decreases tumor volume by over 50% in an HL-60 mouse xenograft model when used at a dose of 4 uMol/kg, i.v., three times per week. JS-K inhibits proliferation, induces apoptosis, and disrupts the cell cycle of Jurkat T acute lymphoblastic leukemia cells. It also induces S-nitrosylation of β-catenin followed by dose-dependent degradation of nuclear β-catenin and S-nitrosylated nuclear β-catenin levels.

2-巯基-5-甲基-1,3,4-噻二唑 99%  腺嘌呤磷酸盐 99%

对羟基苯丙酸 98%  硫酸腺嘌呤 用于细胞培养，98%

酪胺 98%  硫酸腺嘌呤 98%（HPLC）

盐酸酪胺 98%  硫酸腺嘌呤 用于植物细胞培养，98%

乙酸钡 AR，99%  6-氯嘌呤 99%

乙酸钡 99.99% metals basis  胞嘧啶核苷 99%

COH-SR425 mg 50 mg 100 mg>99.00%Cas No. 73439-19-7C13H8Cl4N2O

NVS-PI3-45 mg 10 mg 25 mg>99.00%Cas No. 941580-60-5C20H26N4O3S

NHC-triphosphate5mg 10mg>99.00%Cas No. 34973-27-8C9H16N3O15P3

PD 0332991-d8500μg 1mg>99.00%Cas No. 1628752-83-9C24H21D8N7O2

Rebeccamycin500μg 2.5mg>99.00%Cas No. 93908-02-2C27H21Cl2N3O7

Steffimycin B1mg 5mg>99.00%Cas No. 54526-94-2C29H32O13

Topotecan-d6500μg 1mg>99.00%Cas No. 1044904-10-0C23H17D6N3O5