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Gamma-glutamylcysteine (TFA)

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产品名称: Gamma-glutamylcysteine (TFA)
产品型号: GOY-Y2439
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-27

简单介绍

Gamma-glutamylcysteine (TFA)Soluble in DMSO


Gamma-glutamylcysteine (TFA)  的详细介绍

性能参数

产品名称

Gamma-glutamylcysteine (TFA)

规格

1mg 5mg

货号

GOY-Y2439

 含量

>98.00%

CAS

Cas No. 283159-88-6

别名

N/A

 

 

化学名

N/A

分子式

C10H15F3N2O7S

分子量

分子量 364.3

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

 

用途

仅供科研

价格

电询

详细内容

Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes[1]. IL-10 IL-6 IL-1β TNF-α

[1]. Braidy N, et al. The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes. Front Aging Neurosci. 2019 Aug 8;11:177.

 

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