Ganglioside GM3 Mixture (sodium salt)
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产品名称:
Ganglioside GM3 Mixture (sodium salt)
产品型号:
GOY-Y2425
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-27
简单介绍
Ganglioside GM3 Mixture (sodium salt)Water: Soluble
Ganglioside GM3 Mixture (sodium salt)
的详细介绍
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性能参数
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产品名称
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Ganglioside GM3 Mixture (sodium salt)
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规格
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1mg
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货号
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GOY-Y2425
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含量
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>98.00%
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CAS
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Cas No. 54827-14-4
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别名
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N/A
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化学名
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N/A
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分子式
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C59H107N2O21?Na (for Sphingosine C18:1)
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分子量
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分子量 1180.5
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溶解度
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Water: Soluble
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance in adipocytes. Ganglioside GM3 mixture contains ganglioside GM3 molecular species with C18:1 and C20:1 fatty acyl chains.
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