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Geniposidic acid

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产品名称: Geniposidic acid
产品型号: GOY-Y2393
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-27

简单介绍

Geniposidic acid≥ 14.2mg/mL in DMSO


Geniposidic acid  的详细介绍

性能参数

产品名称

Geniposidic acid

规格

10mM (in 1mL DMSO) 20mg

货号

GOY-Y2393

 含量

>98.00%

CAS

Cas No. 27741-01-1

别名

 

 

 

化学名

(1S,4aS,7aS)-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid

分子式

C16H22O10

分子量

分子量 374.34

溶解度

≥ 14.2mg/mL in DMSO

储存条件

 

General tips

 

用途

仅供科研

价格

电询

详细内容

Geniposidic acid is an effective anticancer and radioprotection agent.Target: OthersMice were given an intraperitoneal injection of Geniposidic acid (GA) (12.5, 25, 50 mg/kg) 1 h before receiving GA against d-galactosamine (GalN) (800 mg/kg)/LPS (40 μg/kg). Liver and blood samples were collected 1 and 8 h after GalN/LPS injection. The survival rate of the GA group was significantly higher than the control. GalN/LPS increased serum aminotransferase activity, serum tumor necrosis factor-α level and hepatic lipid peroxidation and decreased hepatic glutathione content [1]. GA enhanced significantly the postirradiation responses of splenic blastogenesis by PHA. In addition, GA is a potent tumor growth inhibitor when combined with the X-irradiation, though there was no significant synergetic effect on their combined antitumor activity. The preliminary results of GA on hematological and blastogenic observations in this study suggested that it may very well, partially, play a role in an effective anticancer product with the ability to decrease undesirable radiation damage to the hematologic tissue after high dose irradiation [2].

 

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