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Hexamethonium Bromide

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产品名称: Hexamethonium Bromide
产品型号: GOY-Y2386
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-27

简单介绍

Hexamethonium Bromide≥ 36.6mg/mL in H2O, ≥ 36.3mg/mL in DMSO with gentle warming, ≥ 36.2mg/mL in EtOH with gentle warming


Hexamethonium Bromide  的详细介绍

性能参数

产品名称

Hexamethonium Bromide

规格

50mg

货号

GOY-Y2386

 含量

>98.00%

CAS

Cas No. 55-97-0

别名

 

 

 

化学名

trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;dibromide

分子式

C12H30N2.2Br

分子量

分子量 362.19

溶解度

≥ 36.6mg/mL in H2O, ≥ 36.3mg/mL in DMSO with gentle warming, ≥ 36.2mg/mL in EtOH with gentle warming

储存条件

Store at -20°C

General tips

 

用途

仅供科研

价格

电询

详细内容

Hexamethonium Bromide is a non-depolarising ganglionic blocker, a nicotinic nACh (NN) receptor antagonist.Target: nAChRHexamethonium Bromide is a non-depolarising ganglionic blocker, a nicotinic nACh receptor antagonist that acts in autonomic ganglia by binding mostly in or on the NN receptor, and not the acetylcholine binding site itself. It does not have any effect on the muscarinic acetylcholine receptors (mAChR) located on target organs of the parasympathetic nervous system but acts as antagonist at the nicotinic acetylcholine receptors located in sympathetic and parasympathetic ganglia (NN). Hexamethonium Bromide is a nicotinic acetyl choline receptor antagonist. Induces apoptosis and inhibits the stimulatory effect of nicotine on endothelial cell DNA synthesis and proliferation. Hexamethonium bromide hydrate is an inhibitor of AChR α3 [1-3].

 

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