Hexamethonium Bromide
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产品名称:
Hexamethonium Bromide
产品型号:
GOY-Y2386
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-27
简单介绍
Hexamethonium Bromide≥ 36.6mg/mL in H2O, ≥ 36.3mg/mL in DMSO with gentle warming, ≥ 36.2mg/mL in EtOH with gentle warming
Hexamethonium Bromide
的详细介绍
性能参数
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产品名称
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Hexamethonium Bromide
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规格
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50mg
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货号
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GOY-Y2386
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含量
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>98.00%
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CAS
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Cas No. 55-97-0
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别名
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化学名
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trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;dibromide
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分子式
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C12H30N2.2Br
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分子量
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分子量 362.19
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溶解度
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≥ 36.6mg/mL in H2O, ≥ 36.3mg/mL in DMSO with gentle warming, ≥ 36.2mg/mL in EtOH with gentle warming
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Hexamethonium Bromide is a non-depolarising ganglionic blocker, a nicotinic nACh (NN) receptor antagonist.Target: nAChRHexamethonium Bromide is a non-depolarising ganglionic blocker, a nicotinic nACh receptor antagonist that acts in autonomic ganglia by binding mostly in or on the NN receptor, and not the acetylcholine binding site itself. It does not have any effect on the muscarinic acetylcholine receptors (mAChR) located on target organs of the parasympathetic nervous system but acts as antagonist at the nicotinic acetylcholine receptors located in sympathetic and parasympathetic ganglia (NN). Hexamethonium Bromide is a nicotinic acetyl choline receptor antagonist. Induces apoptosis and inhibits the stimulatory effect of nicotine on endothelial cell DNA synthesis and proliferation. Hexamethonium bromide hydrate is an inhibitor of AChR α3 [1-3].
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