性能参数 |
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产品名称 |
Cinnamamide |
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规格 |
5g 25g |
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货号 |
GOY-Y2326 |
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含量 |
>95.00% |
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CAS |
621-79-4 |
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别名 |
N/A |
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化学名 |
N/A |
分子式 |
C9H9NO |
分子量 |
分子 147.2 |
溶解度 |
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml,Ethanol: 5 mg/ml |
储存条件 |
Store at -20°C |
General tips |
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用途 |
仅供科研 |
价格 |
电询 |
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详细内容 |
Cinnamamide is an amide form of of trans-cinnamic acid and a metabolite of Streptomyces. Cinnamamide exhibits low cytotoxicity against BEL-7402 human hepatoma cells and HT-1080 fibrosarcoma cells and inhibits cell growth (IC50s = 1.94 and 1.29 mM, respectively). In vivo, cinnamamide (40 and 100 mg/kg, i.p.) reduces tumor weight in a mouse model of C26 murine colon carcinoma. Cinnamamide (75 and 150 mg/kg, i.p.) also reduces tumor weight in a mouse model of murine hepatoma 22 by 42% and 49%, respectively, without reducing body weight when delivered one or three days following tumor implantation. When presented with cinnamamide-treated food at a concentration of 0.8% w/w, house and wood mice food consumption is reduced to 32% and 17% of pretreatment levels, respectively, however, wood mouse consumption returns to pretrial levels by day two. |
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