性能参数

产品名称

Curcumin-d6

规格

500μg 1mg 5mg

货号

GOY-Y2314

 含量

>99.00%

CAS

1335198-02-1

别名

N/A

化学名

N/A

分子式

C21H14D6O6

分子量

分子 374.4

溶解度

0.1 M NaOH: >3 mg/ml,Acetone: >20 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin by GC- or LC-MS. Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities. It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells. Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells. In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate in mouse skin. Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.

pH7.0氯化钠-蛋白胨缓冲液 BR  盐酸石蒜碱 96%(HPLC)

大豆蛋白胨 BR  维生素K1 98%

胰蛋白胨 BR  磷酸二氢铵 AR，99%

胰蛋白胨大豆肉汤 BR  磷酸二氢铵 CP，98.5%

胰蛋白胨大豆琼脂培养基 BR  磷酸二氢铵 SP

胰化大豆琼脂 BR  磷酸二氢铵 ≥99.99% metals basis

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