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Celecoxib-d7

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产品名称: Celecoxib-d7
产品型号: GOY-Y2311
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-27

简单介绍

Celecoxib-d7DMSO: 76 mg/ml,Ethanol: 33 mg/ml


Celecoxib-d7  的详细介绍

性能参数

产品名称

Celecoxib-d7

规格

500 μg 1 mg 5 mg

货号

GOY-Y2311

 含量

>99.00%

CAS

544686-21-7

别名

N/A

 

 

化学名

N/A

分子式

C17H7D7F3N3O2S

分子量

分子 388.4

溶解度

DMSO: 76 mg/ml,Ethanol: 33 mg/ml

储存条件

Store at -20°C

General tips

 

用途

仅供科研

价格

电询

详细内容

1.Uddin, J.M., Rao, P.N.P., and Knaus, E.E.Design and synthesis of novel celecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: Replacement of the sulfonamide pharmacophore by a sulfonylazide bioisostereBioorg. Med. Chem.11(23)5273-5280(2003) 2.Mardini, I.A., and Fitzgerald, G.A.Selective inhibitors of cyclooxygenase-2: A growing class of anti-inflammatory drugsMolecular Interventions1(1)30-38(2001) 3.Jendrossek, V., Handrick, R., and Belka, C.Celecoxib activates a novel mitochondrial apoptosis signaling pathwayThe FASEB Journal171547-1549(2003) 4.Leahy, K.M., Ornberg, R.L., Wang, Y., et al.Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivoCancer Research62625-631(2002) 5.Zhu, J., Huang, J.W., Tseng, P.H., et al.From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitorsCancer Res.644309-4318(2004) 6.Blobaum, A.L., and Marnett, L.J.Structural and functional basis of cyclooxygenase inhibitionJ. Med. Chem.50(7)1425-1441(2007)

 

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