BMSpep-57 hydrochloride
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产品名称:
BMSpep-57 hydrochloride
产品型号:
GOY-Y2299
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-27
简单介绍
BMSpep-57 hydrochlorideN/A
BMSpep-57 hydrochloride
的详细介绍
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性能参数
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产品名称
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BMSpep-57 hydrochloride
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规格
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1 mg
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货号
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GOY-Y2299
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含量
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>99.00%
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CAS
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N/A
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别名
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N/A
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化学名
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N/A
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分子式
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C89H127ClN24O19S
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分子量
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分子 1904.63
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溶解度
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N/A
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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In a ELISA competition assay, BMSpep-57 inhibits PD-1/PD-L1 binding up to 98.1% 300 nM. And it shows a concentration dependent inhibition of PD-1/PD-L1 binding with an IC50 of 7.68 nM[1].BMSpep-57 induced high levels of IL-2 at 1 μM and 500 nM concentrations in SEB-stimulated peripheral blood mononuclear cells[1].BMSpep-57 (0.2-10 μM; 24 hours) does not show any effect on the Jurkat, CHO and HepG2 cells’ viability at the various concentrations tested[1].
[1]. Aravindhan Ganesan, et al. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors.Sci Rep . 2019 Aug 27;9(1):12392.
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