性能参数

产品名称

Danshensu (Dan shen suan A)

规格

10mM*1mLinWater 50mg 100mg

货号

GOY-Y2212

 含量

>98.00%

CAS

76822-21-4

别名

N/A

化学名

N/A

分子式

C9H10O5

分子量

分子 198.17

溶解度

H2O : 6.2 mg/mL (31.29 mM)

储存条件

Store at 4°C

General tips

用途

仅供科研

价格

电询

详细内容

Danshensu (DSS) significantly decreases the level of the marker enzymes (creatine kinase and lactate dehydrogenase) from the coronary effluents and myocardial infarction size. This could markedly contribute to the recovery of cardiac function after I/R injury. DSS also has ROS scavenging activity and boosts endogenous antioxidants such as SOD, CAT, MDA, GSH-PX and HO-1 activities by activating nuclear factor erythroid-2-related factor 2 (Nrf2) signaling pathway which is mediated by Akt and ERK1/2 in western blot analysis[2].

Acute treatment with a single dose of danshensu in rats with normal tHcy does not change plasma tHcy. In contrast, danshensu significantly lowers tHcy in rats with elevated tHcy. The relatively higher cysteine and glutathione levels after treatment with danshensu indicates that its tHcy-lowering effect is via increased activity of the trans-sulphuration pathway[1].

[1]. YG Cao, et al. Beneficial effects of danshensu, an active component of Salvia miltiorrhiza, on homocysteine metabolism via the trans-sulphuration pathway in rats. Br J Pharmacol. 2009 Jun; 157(3): 482-490. [2]. Yu J, et al. Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling. Int J Clin Exp Med. 2015 Sep 15;8(9):14793-804.

1,2－二氯乙烷(氘4) D,99%  碳酸锶 CP,97%

十氢化萘-d18 D,99%  碳酸锶 99.995% metals basis

1，2-二溴乙烷 D,99%  氟化锶 99.99% metals basis

氚代二氧六环 D,99%  氟化锶 CP，98%

氘代乙醇-d6 99.5 atom % D  磷酸氢锶 荧光级，99%

氘代乙醇 D,99% anhydrous  磷酸氢锶 99.98% metals basis

IQ-1S free acid5mg 10mg 25mg 50mg 100mg>98.00%Cas No. 23146-22-7C15H9N3O

Longdaysin5mg 10mg 25mg 50mg 100mg>98.00%Cas No. 1353867-91-0C16H16F3N5

LM22B-102mg 5mg 10mg 50mg 100mg>98.00%Cas No. 342777-54-2C27H33ClN2O4

Magnolin10mM*1mLinDMSO 5mg 10mg 25mg 50mg>98.00%Cas No. 31008-18-1C23H28O7

LY32149961mg 5mg 10mg 50mg 100mg>98.00%Cas No. 1951483-29-6C22H27N7O2S

NCB-08465mg 10mg 25mg 50mg 100mg>98.00%Cas No. 1792999-26-8C21H21N5O2

Mogrol10mM*1mLinDMSO 1mg 5mg 10mg 25mg>98.00%Cas No. 88930-15-8C30H52O4