性能参数

产品名称

Dacarbazine

规格

10mM (in 1mL DMSO) 200mg 1g

货号

GOY-Y2207

 含量

>98.00%

CAS

4342/3/4

别名

化学名

(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide

分子式

C6H10N6O

分子量

分子 182.18

溶解度

≥ 2.3mg/mL in DMSO, ≥ 0.54 mg/mL in H2O, <0.49 mg/mL in EtOH

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Dacarbazine is commonly used as a single agent in the treatment of metastatic melanoma in middle of 2006, and as part of the ABVD chemotherapy regimen to treat Hodgkin lymphoma, and in the MAID regimen for sarcoma.Currently, Dacarbazine combined with Oblimersen for the treatment of malignant melanoma in clinical trials.[3]Dacarbazine is normally administered by injection (a shot) or intravenous infusion (IV) under the immediate supervision of a doctor or nurse.Now in phase III about Melanoma Recurrent 2015 March.

References:1. "Alkylating Agents". US National Library of Medicine. Retrieved 2 August 2014.

2. Wiedemann GJ. et al. "Ifosfamide, carboplatin and etoposide (ICE) combined with 41.8 degrees C whole body hyperthermia in patients with refractory sarcoma". European Journal of Cancer 1996,32A (5): 888–92.

3. MedLine, U.S. National Institutes of Health, National Library of Medicine.

4. CClinicalTrials.gov Identifier:NCT02288897.

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木托盘

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