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CDK/CRK Inhibitor

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产品名称: CDK/CRK Inhibitor
产品型号: GOY-Y2147
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-26

简单介绍

Cinobufagin≥ 16.65mg/mL in DMSO


CDK/CRK Inhibitor  的详细介绍

性能参数

产品名称

Cinobufagin

规格

10mM (in 1mL DMSO) 20mg

货号

GOY-Y2147

 含量

>98.00%

CAS

470-37-1

别名

 

 

 

化学名

(1R,2R,2aR,3aS,3bR,5aR,7S,9aS,9bS,11aR)-7-hydroxy-9a,11a-dimethyl-1-(2-oxo-2H-pyran-5-yl)hexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-2-yl acetate

分子式

C26H34O6

分子量

分子 442.54

溶解度

≥ 16.65mg/mL in DMSO

储存条件

 

General tips

 

用途

仅供科研

价格

电询

详细内容

References:

[1]. Zhang G, et al. Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells. Oncotarget. 2016 Mar 3.

[2]. Yu Y, et al. Immunomodulatory Effects of Cinobufagin on Murine Lymphocytes and Macrophages. Evid Based Complement Alternat Med. 2015;2015:835263.

[3]. Baek SH, et al. Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway. Immunopharmacol Immunotoxicol. 2015 Jun;37(3):265-73.

[4]. Jiun-Yih Yeh, et al. Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells. The ProstateVolume 54, Issue 2, pages 112–124, 1 February 2003

[5]. Yu CH, et al. Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells. Cancer Science, 2008, 99 (12): 2467-2476

[6]. Peng Bei, et al. Progress in study on basic and clinical application in treating liver cancer by Cinobufagin Injection. Drug Evaluation Research, 2011-01

 

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