性能参数

产品名称

Calcimycin hemimagnesium

规格

1mg 5mg

货号

GOY-Y2129

 含量

>98.00%

CAS

72124-77-7

别名

N/A

化学名

N/A

分子式

C58H72MgN6O12

分子量

分子 1069.53

溶解度

N/A

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Calcimycin (A-23187) hemimagnesium mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner[4].

Calcimycin (A-23187) hemimagnesium (2.5 or 7.5 nM; intrapleurally) induces protein leakage[5]. Animal Model: Mice (ICR, 25-30 g)[5]

[1]. Wu Q, et al. Characterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin(A23187) in Streptomyces chartreusis NRRL 3882. Antimicrob Agents Chemother. 2011 Mar;55(3):974-82. [2]. Elliott JI, et al. IKCa1 activity is required for cell shrinkage, phosphatidylserine translocation and death in Tlymphocyte apoptosis. EMBO Rep. 2003 Feb;4(2):189-94. [3]. Engedal N, et al. Modulation of intracellular calcium homeostasis blocks autophagosome formation. Autophagy. 2013 Oct;9(10):1475-90. [4]. Mawatwal S, et al. Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner. Biochim Biophys Acta Gen Subj. 2017 Dec;1861(12):3190-3200. [5]. Wang JP, et al. Effect of norathyriol, isolated from Tripterospermum lanceolatum, on A23187-induced pleurisy and analgesia in mice. Naunyn Schmiedebergs Arch Pharmacol. 1994 Jul;350(1):90-5.

邻苯二甲酸丁苄酯标准溶液 1000μg/ml，溶剂：甲醇  环庚三烯酚酮 98%

邻苯二甲酸丁苄酯 98%  2-氨基-5-氯-2'-氟二苯甲酮 98%

过氧化氢异丙苯 80-85 %  2-氨基-5-溴-2'-氟二苯甲酮 98%

过氧化环己酮  50%邻苯二甲酸二辛酯溶液  α-溴邻甲基苯甲腈 98%

硬脂酸钙 Ca 6.6-7.4%  11-溴十一酸 98%

二苯甲酸二聚丙二醇酯 80%  11-溴十一醇 98%

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