性能参数

产品名称

Demethylzeylasteral

规格

10mM*1mL in DMSO 1mg 5mg 10mg 20mg

货号

GOY-Y2097

 含量

>98.00%

CAS

107316-88-1

别名

N/A

化学名

N/A

分子式

C29H36O6

分子量

分子 480.59

溶解度

DMSO: 250 mg/mL (520.19 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Demethylzeylasteral is a triterpene compound isolated from Tripterygium wilfordii Hook F, with anti-inflammatory, immunosuppressive and anti-tumor activities[1][2][3][4][5]. Demethylzeylasteral can significantly alleviates atherosclerosis (AS)[5]. Demethylzeylasteral inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways[2].

[1]. Zhang K, et al. Demethylzeylasteral inhibits glioma growth by regulating the miR-30e-5p/MYBL2 axis. Cell Death Dis. 2018 Oct 10;9(10):1035. [2]. Li L, et al. Demethylzeylasteral (T-96) inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways. Naunyn Schmiedebergs Arch Pharmacol. 2019 May;392(5):593-603. [3]. Wang Q, et al. Demethylzeylasteral ameliorates inflammation in a rat model of unilateral ureteral obstruction through inhibiting activation of the NF?κB pathway. Mol Med Rep. 2017 Jul;16(1):373-379. [4]. Zhao Y, et al. Demethylzeylasteral inhibits cell proliferation and induces apoptosis through suppressing MCL1 in melanoma cells. Cell Death Dis. 2017 Oct 26;8(10):e3133. [5]. Experimental study of the anti-atherosclerotic effect of demethylzeylasteral. Exp Ther Med. 2017 Jun;13(6):2787-2792.

溴氯甲烷 99.5%  1,3,5-**基吡唑  97%

3-溴-1-丙醇 97%  香兰素胺盐酸盐 99%

3-溴苯甲醛 97%  辣椒素 97%

2-二乙氨基氯乙烷盐酸盐 99%  辣椒素 分析标准品，>98%

2-氯吡啶 99%  砷  99.995% metals basis

2-氯异氰酸乙酯 97%  三氧化二砷 AR（剧毒品）

SRS11-921mg 5mg 10mg 25mg>98.00%Cas No. 1467047-25-1C22H28N2O2

SR 168321mg 5mg 10mg 25mg>98.00%Cas No. 2088135-12-8C17H12ClN3O4

SPK-60110mg 50mg 100mg 200mg>98.00%Cas No. 1096687-52-3C11H15KOS2

SPI 11225mg 50mg 100mg 250mg>98.00%Cas No. 1051387-90-6C22H17FN4O5S

Stearamide100mg 250mg 500mg 1g>98.00%Cas No. 124-26-5C18H37NO

Talarozole R enantiomer5mg 10mg 25mg 50mg>98.00%Cas No. 870093-23-5C21H23N5S

Tadalafil10mM (in 1mL DMSO) 50mg 100mg 500mg>98.00%Cas No. 171596-29-5C22H19N3O4