性能参数

产品名称

dMCL1-2

规格

100mg 250mg 500mg

货号

GOY-Y2064

 含量

>98.00%

CAS

2351218-88-5

别名

N/A

化学名

N/A

分子式

C61H66N10O12S

分子量

分子 1163.3

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1[1]. KD: 30 nM (MCL1)[1]

[1]. Papatzimas JW, et al. From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1). J Med Chem. 2019 Jun 13;62(11):5522-5540.

1-(**基硅基)丙炔 98%  三乙烯四胺 色谱固定液

2-(**基硅基)噻唑 96%  甲苯二异氰酸酯 Standard for GC（剧毒品）

**基硅烷基甲磺酸盐 97%  乙酸乙烯酯 Standard for GC, ≥99.5% (GC)

氨甲基**基硅烷 98%  邻二甲苯 Standard for GC,≥99% (GC)

1-**硅基-1-戊炔 98%  二苯基乙酸 98%

3-(**基硅基)丙炔醇 98%  1,3-丙酮二羧酸二乙酯 95%

LX2761100mg 250mg 500mg>98.00%Cas No. 1610954-97-6C32H47N3O6S

Lysophosphatidylethanolamines (egg)5mg 10mg 50mg>98.00%Cas No. 97281-40-8N/A

MCH-1 antagonist 11mg 5mg 10mg>98.00%Cas No. 1039825-68-7C25H26N4O2

Microcystin-LA25μg 100μg 500μg>98.00%Cas No. 96180-79-9C46H67N7O12

Methyl α-Linolenyl Fluorophosphonate1mg 5mg 10mg>98.00%Cas No.C19H34FO2P

ML-2981mg 5mg 10mg>98.00%Cas No. 1426916-02-0C22H23F3N4O2