性能参数 |
|||
产品名称 |
Echinosporin |
||
规格 |
1 mg |
||
货号 |
GOY-Y2027 |
||
含量 |
>98.00% |
||
CAS |
79127-35-8 |
||
别名 |
N/A |
|
|
化学名 |
N/A |
分子式 |
C10H9NO5 |
分子量 |
分子 223.2 |
溶解度 |
DMF: soluble,Methanol: soluble,Water: soluble |
储存条件 |
Store at -20°C |
General tips |
|
用途 |
仅供科研 |
价格 |
电询 |
|
|||
详细内容 |
Echinosporin is a bacterial metabolite originally isolated from Streptomyces echinosporus that has antibacterial and anticancer activities.1,2,3 It is active against P. vulgaris, S. typhosa, S. sonnei, E. coli, and B. subtilis (MICs = 100, 100, 100, 200, and 400 μg/ml, respectively).1 Echinosporin induces cell cycle arrest at the G2/M phase and apoptosis in, as well as inhibits proliferation of, HCT-15 human colorectal cancer cells (IC50s = 1.7, 1.75, and 247 μM, respectively).2 It inhibits tumor growth in murine P388 leukemia and Meth 1 fibrosarcoma models when administered at doses ranging from 10 to 80 mg/kg.3 1.Sato, T., Kawamoto, I., Oka, T., et al.A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterizationJ. Antibiot. (Tokyo)35(3)266-271(1982) 2.Cui, C.B., Liu, H.B., Gu, J.Y., et al.Echinosporins as new cell cycle inhibitors and apoptosis inducers from marine-derived Streptomyces albogriseolusFitoterapia78(3)238-240(2007) 3.Morimoto, M., and Imai, R.Antitumor activity of echinosporinJ. Antibiot. (Tokyo)38(4)490-495(1985) |
公司正在销售的产品:
二溴甲烷 99% 硫代乙酸 95% 1,3-二溴丙烷 98% 氧化亚锡 AR,99% 1,3-二溴丙烷 99% 氧化亚锡 99.9% metals basis 1,4-二溴丁烷 98% 锡酸钠 CP,53.67% SnO2 1,5-二溴戊烷 98% 锡酸钠 AR,55.3% SnO2 1,6-二溴己烷 97% 二氧化锡 AR,99.5% |
β-Muricholic Acid-d41 mg>99.00%Cas No. N/AC24H36D4O5 α-Muricholic Acid-d41 mg>99.00%Cas No. N/AC24H36D4O5 α-Linolenic Acid-d5 MaxSpec? Standard100μg>99.00%Cas No. 145191-04-4C18H25D5O2 (±)-Climbazole-d41mg>99.00%Cas No. 1185117-79-6C15H13ClD4N2O2 13-cis-Retinoic Acid-d51 mg>99.00%Cas No. 78996-15-3C20H23D5O2 Acesulfame-d4 (potassium salt)1 mg>99.00%Cas No. 1623054-53-4C4D4NO4S.K |
传真号码:021-39596320 021-39921927
QQ: 3004918891 3004905818 3004901493
移动电话:18321818584 15026555973
地址:上海松江新砖公路1155号
产品均为实验试剂,仅供科研实验使用,非药品、非食品、不可用于动物及人体!