性能参数
产品名称
DPBQ
规格
5 mg
货号
GOY-Y2025
含量
>98.00%
CAS
7029-89-2
别名
N/A
化学名
分子式
C24H14N2O2
分子量
分子 362.38
溶解度
Soluble in DMSO
储存条件
Store at -20°C
General tips
用途
仅供科研
价格
电询
详细内容
DPBQ is a p53 activator.
DPBQ elicits apoptosis and cell death and is selective for effects in 4N cells. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells. Knockdown of TP53 restores proliferation of tetraploid cells in the presence of DPBQ[1].
[1]. Choudhary A, et al. Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer. Mol Cancer Ther. 2016 Jan;15(1):48-59.
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