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(-)-α-Bisabolol

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产品名称: (-)-α-Bisabolol
产品型号: GOY-Y1975
产品展商: 谷研
产品文档: 无相关文档
发布时间:2023-04-25

简单介绍

(-)-α-BisabololDMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml


(-)-α-Bisabolol  的详细介绍

性能参数

产品名称

(-)-α-Bisabolol

规格

1mg 5mg 10mg 25mg

货号

GOY-Y1975

 含量

>95.00%

CAS

23089-26-1

别名

N/A

 

 

化学名

N/A

分子式

C15H26O

分子量

分子 222.4

溶解度

DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml

储存条件

Store at 2-8°C

General tips

 

用途

仅供科研

价格

电询

详细内容

(-)-α-Bisabolol is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, including C. sativa, C. indica, and C. sativa/C. indica hybrid strains, with diverse biological activities. It inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively). It also reduces the growth of L. infantum and L. donovani amastigotes (IC50s = 56.9 and 39.4 μM, respectively) with a cytotoxic concentration (CC50) value of greater than 1,000 μM in L929 cells. In vivo, (-)-α-bisabolol (200 mg/kg) reduces parasite load in the liver and spleen in a mouse model of visceral leishmaniasis. (-)-α-Bisabolol (200 mg/kg) reduces the size of ethanol-induced lesions, decreases malondialdehyde (MDA) production, and increases superoxide dismutase (SOD) activity in gastric mucosa in mice. It also decreases serotonin-, carrageenan-, and dextran-, but not histamine-, induced paw edema as well as acetic-acid induced writhing and paw-licking time in the formalin test in mice, indicating anti-inflammatory and antinociceptive activity.

 

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