性能参数

产品名称

(-)-Chaetominine

规格

500μg 2.5mg

货号

GOY-Y1944

 含量

>95.00%

CAS

918659-56-0

别名

N/A

化学名

N/A

分子式

C22H18N4O4

分子量

分子 402.4

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

(-)-Chaetominine is a cytotoxic alkaloid originally isolated from Chaetomium sp. IFB-E015. It inhibits the growth of K562 leukemia and SW1116 colon cancer cells (IC50s = 20 and 28 nM, respectively). (-)-Chaetominine induces apoptosis of K562 cells via upregulation of the Bax/Bcl-2 ratio, decreasing mitochondrial membrane potential, inducing mitochondrial cytochrome C release, and activation of caspase-3 and caspase-9. It also decreases doxorubicin efflux mediated by multidrug resistance-associated protein 1 (MRP1) and restores sensitivity to doxorubicin in resistant K562 cells.

对异丙基苯酚 98%  丹酚酸A  分析标准品，≥98%

4-异丙基苯硫酚 96%  丁香酸 98%

2-异丙基苯硫酚 90%  D(-)-水杨苷 98%

2-碘-5-甲基噻吩 97%  D(-)-水杨苷 分析标准品，≥98%

3-碘硝基苯 99%  青藤碱 97%

异烟碱 99%  丁香醛 98%

α-Amanitin1mg>95.00%Cas No. 23109-05-9C39H54N10O14S

Trichostatin C500μg 2.5mg>95.00%Cas No. 68676-88-0C23H32N2O8

Valproic Acid Acyl-D-Glucuronide500μg 1mg>95.00%Cas No. N/AC14H24O8

Tubastatin A (trifluoroacetate salt)1mg 5mg 10mg>95.00%Cas No. 1239262-52-2C20H21N3O2?CF3COOH

TSI-011mg 5mg 10mg 25mg>95.00%Cas No. 704878-75-1C14H11Cl2NO4

UNC2170 (maleate)1mg 5mg 10mg 25mg>95.00%Cas No. N/AC14H21BrN2O?C4H4O4