性能参数

产品名称

4-bromo A23187

规格

1mg 5mg 10mg

货号

GOY-Y1891

 含量

>98.00%

CAS

76455-48-6

别名

4-Bromocalcimycin

化学名

6-bromo-5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid

分子式

C29H36BrN3O6

分子量

分子 602.5

溶解度

1mg/mL in DMSO, 10mg/mL in DMF

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187. 4-bromo A23187 is non-fluorescent.[1] As a result, it is often used in experiments where fluorescent probes are employed.[2],[3]

Reference:

[1]. Deber, C.M., Tom-Kun, J., Mack, E., et al. Bromo-A23187: A nonfluorescent calcium ionophore for use with fluorescent probes. Anal.Biochem. 146(2), 349-352 (1985).

[2]. Ducreux, S., Gregory, P., and Schwaller, B. Inverse regulation of the cytosolic Ca2+ buffer parvalbumin and mitochondrial volume in muscle cells via SIRT1/PGC-1α axis. PLoS One 7(9), (2012).

[3]. Yang, J., Singh, V., Cha, B., et al. NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells. J.Biol.Chem. 288(23), 16960-16974 (2013).

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